Paola Ballerini Selected Research

Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic)

1/2017	ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.
11/2012	An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.
8/2012	Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
2/2006	Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

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Paola Ballerini Research Topics

Disease

13	Leukemia 01/2022 - 04/2011
12	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 08/2002
11	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2021 - 08/2002
4	Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic) 01/2017 - 02/2006
2	Neoplasms (Cancer) 12/2021 - 01/2021
2	Thrombocytopenia (Thrombopenia) 12/2021 - 01/2021
1	Congenital amegakaryocytic thrombocytopenia 12/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Hemorrhage 01/2021
1	B-Cell Leukemia (Leukemia, B Cell) 01/2019
1	Thrombosis (Thrombus) 11/2018
1	Thrombocytosis (Thrombocythemia) 12/2016
1	Polyploidy 08/2012
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2006
1	Down Syndrome (Down's Syndrome) 02/2006
1	Genetic Translocation (Chromosomal Translocation) 11/2004

Drug/Important Bio-Agent (IBA)

6	Transcription Factors (Transcription Factor)IBA 01/2021 - 08/2002
2	Thrombopoietin (c-mpl Ligand)IBA 12/2021 - 12/2016
2	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 09/2017
2	CytokinesIBA 11/2019 - 06/2014
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2018 - 01/2018
2	LigandsIBA 11/2018 - 02/2009
2	Proteins (Proteins, Gene)FDA Link 11/2012 - 02/2006
1	AntigensIBA 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2022
1	CalreticulinIBA 12/2021
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2021
1	eltrombopag FDA Link 01/2021
1	NVP-BEP800IBA 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	src-Family KinasesIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	TOR Serine-Threonine KinasesIBA 01/2021
1	trametinibIBA 01/2020
1	Interleukin-7 (Interleukin 7)IBA 11/2019
1	Tyrosine Kinase InhibitorsIBA 10/2019
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 01/2019
1	chondroitin sulfate proteoglycan 4IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	convulxinIBA 11/2018
1	CollagenIBA 11/2018
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 11/2018
1	EphrinsIBA 11/2018
1	LipidsIBA 01/2018
1	saracatinibIBA 01/2018
1	Cytarabine (Cytosar-U)FDA LinkGeneric 09/2017
1	Homeodomain Proteins (Proteins, Homeobox)IBA 05/2017
1	MicroRNAs (MicroRNA)IBA 05/2017
1	Oncogene Proteins (Oncogene Protein)IBA 01/2017
1	4,5,6,7- tetrahydroisoxazolo(4,5- c)pyridin- 3- ol (THPO)IBA 12/2016
1	Interleukin-18 ReceptorsIBA 06/2014
1	Interleukin-18 (Interleukin 18)IBA 06/2014
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2014
1	Conditioned Culture MediaIBA 06/2014
1	MLN 8237IBA 08/2012
1	Aurora Kinase AIBA 08/2012
1	Phosphotransferases (Kinase)IBA 08/2012
1	Small Interfering RNA (siRNA)IBA 04/2011
1	Biological ProductsIBA 02/2009
1	Notch ReceptorsIBA 02/2009
1	GATA1 Transcription FactorIBA 02/2006

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 01/2021 - 09/2017
2	Transplantation 07/2016 - 01/2016
2	Therapeutics 06/2014 - 04/2006
1	Aftercare (After-Treatment) 01/2021
1	Platelet Transfusion (Blood Platelet Transfusions) 01/2021
1	Immunotherapy 01/2020